Release 57
(Aug 26, 2025)

Whole genome analysis for QTL/association enrichment

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Version: Enrich S: beta v0.8
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Data:

Number of disease susceptibility traits:48
Number of QTL / associations found:962
Number of chromosomes where QTL / associations are found:30

Chi-squared (χ2) test: are disease susceptibility traits over-represented on some chromosomes?

Chromosomes Total χ2 df p-values FDR * Size of χ2
Chromosome Z1253.09616291.988325e-2451.988325e-244
Chromosome 111574.29376299e-411.227273e-40
Chromosome 22268.97968299e-411.227273e-40
Chromosome 33297.23760299e-411.227273e-40
Chromosome 47112.88816299e-411.227273e-40
Chromosome 512927.97344299e-411.227273e-40
Chromosome 6255.57408294.216458e-385.499728e-38
Chromosome 7594.76752297.839599e-1071.809138e-106
Chromosome 8123.05040291.492336e-131.721926e-13
Chromosome 914.07744290.99097839.983293e-01
Chromosome 10151.69056291.445625e-181.734750e-18
Chromosome 11339.79872299.851149e-551.847090e-54
Chromosome 12488.58864296.342596e-851.359128e-84
Chromosome 130.00672290.9983293258231159.983293e-01
Chromosome 140.00672290.9983293258231159.983293e-01
Chromosome 15664.32288292.73419e-1216.835475e-121
Chromosome 1636.43056290.16135631.792848e-01
Chromosome 17867.00048299.61243e-1643.604661e-163
Chromosome 18386.40144294.19685e-648.393700e-64
Chromosome 19296.18976294.604972e-468.126421e-46
Chromosome 20796.44720296.41023e-1491.923069e-148
Chromosome 211096.62192293.131684e-2121.879010e-211
Chromosome 221179.15024299.991533e-2307.493650e-229
Chromosome 23796.44720296.41023e-1491.923069e-148
Chromosome 24664.32288292.73419e-1216.835475e-121
Chromosome 251444.69680293.356377e-2861.006913e-284
Chromosome 26183.32496292.431487e-243.039359e-24
Chromosome 271017.08784292.117432e-1951.058716e-194
Chromosome 28940.54704293.080998e-1791.320428e-178
Chromosome 331353.18768291.032118e-2661.548177e-265

Chi-squared (χ2) test: Which of the 48 disease susceptibility traits are over-represented in the QTLdb

Traits Total χ2 df p-values FDR * Size of χ2
Alternative complement activation by BRBC 35.71076 47 0.8855211 1.000000e+00
Antibody response to Brucella abortus 23.19308 47 0.9986134 1.000000e+00
Antibody response to E. coli 31.60743 47 0.958472 1.000000e+00
Antibody response to KLH antigen 125.18665 47 4.971694e-09 4.772826e-08
Antibody response to Mycobacterium butyricum 35.72916 47 0.8850792 1.000000e+00
Antibody response to Newcastle disease virus 26.1171 47 0.9941798 1.000000e+00
Antibody response to SRBC antigen 55.60284 47 0.1824275 4.652089e-01
Antibody response to Salmonella enteritidis 37.46009 47 0.838833 1.000000e+00
Antibody titer to KLH antigen 100.94386 47 8.2217e-06 4.933020e-05
Antibody titer to LPS antigen 30.04093 47 0.9742998 1.000000e+00
Antibody titer to LTA antigen 50.40249 47 0.3404488 7.427974e-01
Antibody titer to Marek's disease virus 114.66916 47 1.393412e-07 1.114730e-06
Antibody titer to Newcastle disease virus 61.86303 47 0.07171951 2.295024e-01
Antibody titer to SRBC antigen 88.61053 47 0.0002317442 1.112372e-03
Antibody titer to avian influenza virus 7.63515 47 1 1.000000e+00
Antibody titer to fowl cholera 52.96045 47 0.2550483 6.121159e-01
Antibody titer to fowl typhoid 68.62632 47 0.02143600 7.914831e-02
Antibody titer to infectious bronchitis virus 29.2315 47 0.9804062 1.000000e+00
Antibody titer to infectious bursal disease virus 36.96892 47 0.8528848 1.000000e+00
Ascites syndrome incidence 52.08334 47 0.2827312 6.462427e-01
Avian influenza susceptibility 22.55994 47 0.9990284 1.000000e+00
Campylobacter intestinal colonization 111.79866 47 3.359967e-07 2.303977e-06
Caseous cecal core 12.5493 47 0.9999999 1.000000e+00
Cecal bacterial burden after challenge with Salmonella E 55.53265 47 0.1841452 4.652089e-01
Cecal bacterial burden after challenge with Salmonella T 344.63049 47 6.498182e-47 3.119127e-45
Cell-mediated immune response 336.19452 47 2.535626e-45 6.085502e-44
Classical complement activation by SRBC 39.59546 47 0.7698021 1.000000e+00
Cloacal bacterial burden after challenge with Salmonella E 39.1098 47 0.7865674 1.000000e+00
Cloacal bacterial burden after challenge with Salmonella T 5.85634 47 1 1.000000e+00
Fecal egg count 36.55103 47 0.864266 1.000000e+00
Fecal oocyst count 47.81748 47 0.4393709 9.169480e-01
Fowl typhoid susceptibility 61.0547 47 0.08176068 2.452820e-01
Immunoglobulin Y level 73.95604 47 0.007283584 2.913434e-02
Interferon-gamma level 42.1 47 0.6753256 1.000000e+00
Liver bacterial burden after challenge with Salmonella E 23.51089 47 0.998353 1.000000e+00
Lymphocyte proliferation 25 47 0.9965063 1.000000e+00
Marek's disease susceptibility 88.84309 47 0.0002183299 1.112372e-03
Oocyst shedding 56.13332 47 0.1698153 4.652089e-01
Parasitic lesions 86.45455 47 0.000400104 1.745908e-03
Plasma coloration 285.5124 47 6.679008e-36 1.068641e-34
Pullorum disease susceptibility 170.29778 47 7.09491e-16 8.513892e-15
Salmonella presence in ovary 20.25001 47 0.9997744 1.000000e+00
Spleen bacterial burden after challenge with Salmonella E 18.20736 47 0.9999517 1.000000e+00
Spleen bacterial burden after challenge with Salmonella T 6.696 47 1 1.000000e+00
Systemic sclerosis incidence 34.44203 47 0.913449 1.000000e+00
Time to achieve maximum antibody response to SRBC 6.696 47 1 1.000000e+00
Viral clearance 43.0197 47 0.6381086 1.000000e+00
Viral load, Newcastle Disease Virus 63.45177 47 0.05496166 1.884400e-01

Correlations found between some of these traits for your reference

No correlation data found on these traits

Overall Test

Data Chi'Square Test Fisher's Exact Test
Number of chrom.:30 χ2=52124.208480
Number of traits:48 df=1363
Number of QTLs:962 p-value=0

FOOT NOTE: * : FDR is short for "false discovery rate", representing the expected proportion of type I errors. A type I error is where you incorrectly reject the null hypothesis, i.e. you get a false positive. It's statistical definition is FDR = E(V/R | R > 0) P(R > 0), where V = Number of Type I errors (false positives); R = Number of rejected hypotheses. Benjamini–Hochberg procedure is a practical way to estimate FDR.

 

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