Release 57
(Aug 26, 2025)

Whole genome analysis for QTL/association enrichment

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Version: Enrich S: beta v0.8
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Data:

Number of disease & injury traits:24
Number of QTL / associations found:1,292
Number of chromosomes where QTL / associations are found:32

Chi-squared (χ2) test: are disease & injury traits over-represented on some chromosomes?

Chromosomes Total χ2 df p-values FDR * Size of χ2
Chromosome X548.44272315.732058e-961.834259e-95
Chromosome 112091.77408319e-411.600000e-40
Chromosome 2390.32496319.146624e-642.251477e-63
Chromosome 316109.80488319e-411.600000e-40
Chromosome 444.21976310.058391397.186633e-02
Chromosome 552.24464310.0098726851.263704e-02
Chromosome 6122.83272317.026687e-139.368916e-13
Chromosome 712.71520310.9984949.984940e-01
Chromosome 8200.70288319.596765e-271.395893e-26
Chromosome 9223.14240315.884677e-319.415483e-31
Chromosome 101.12392310.9983293258231159.984940e-01
Chromosome 1124.15792310.80404789.189118e-01
Chromosome 12623.04336312.286794e-1111.219623e-110
Chromosome 131.12392310.9983293258231159.984940e-01
Chromosome 1441.69352310.095104981.127170e-01
Chromosome 153768.75240319e-411.600000e-40
Chromosome 166139.03104319e-411.600000e-40
Chromosome 17271.58832312.991624e-405.038525e-40
Chromosome 1818.80808310.95803319.984940e-01
Chromosome 19585.14856311.563823e-1036.255292e-103
Chromosome 20122.83272317.026687e-139.368916e-13
Chromosome 21413.50776311.943496e-685.182656e-68
Chromosome 22585.14856311.563823e-1036.255292e-103
Chromosome 23353.17344312.52576e-565.773166e-56
Chromosome 24662.12688311.795726e-1192.873162e-118
Chromosome 25512.92560311.124109e-883.270135e-88
Chromosome 26200.70288319.596765e-271.395893e-26
Chromosome 27548.44272315.732058e-961.834259e-95
Chromosome 28662.12688311.795726e-1192.873162e-118
Chromosome 29623.04336312.286794e-1111.219623e-110
Chromosome 30623.04336312.286794e-1111.219623e-110
Chromosome 31623.04336312.286794e-1111.219623e-110

Chi-squared (χ2) test: Which of the 24 disease & injury traits are over-represented in the QTLdb

Traits Total χ2 df p-values FDR * Size of χ2
Bone fracture 356.67979 23 1.370076e-61 6.576365e-61
Degenerative suspensory ligament desmitis 97.1123 23 4.418161e-11 5.890881e-11
Dwarfism 41.28612 23 0.01098080 1.145823e-02
Equine arteritis virus 703 23 1.035885e-133 2.486124e-132
Equine herpesvirus type 1-induced myeloencephalopathy 48.69232 23 0.001363222 1.487151e-03
Equine metabolic syndrome 76.11901 23 1.333649e-07 1.600379e-07
Equine neuroaxonal dystrophy/degenerative myeloencephalopathy 354.79815 23 3.321695e-61 1.328678e-60
Equine sarcoids 79.6323 23 3.641343e-08 4.599591e-08
Foal Immunodeficiency Syndrome 173.18183 23 5.216174e-25 9.629860e-25
Guttural pouch tympany 690.34962 23 4.783491e-131 5.740189e-130
Hydrocephalus 560.99812 23 6.684471e-104 5.347577e-103
Insect bite hypersensitivity 169.35725 23 2.801114e-24 4.801910e-24
Laminitis 39.37501 23 0.01804012 1.804012e-02
Melanoma 550.7143 23 9.421395e-102 5.652837e-101
Osteochondrosis 138.76812 23 1.565254e-18 2.504406e-18
Osteochondrosis dissecans 274.21549 23 7.125412e-45 2.442998e-44
Overriding spinous processes 232.9091 23 1.213913e-36 3.641739e-36
Recurrent airway obstruction 173.77009 23 4.026052e-25 8.052104e-25
Recurrent exertional rhabdomyolysis 206.78324 23 1.660172e-31 3.984413e-31
Recurrent laryngeal neuropathy 75.87901 23 1.456247e-07 1.664282e-07
Recurrent uveitis 121.57807 23 2.162367e-15 3.243550e-15
Rhodococcus equi infection 183.06258 23 6.632266e-27 1.447040e-26
Vitiligo 109.90866 23 2.618397e-13 3.696560e-13
chronic progressive lymphedema 212.48914 23 1.270489e-32 3.387971e-32

Correlations found between some of these traits for your reference

No correlation data found on these traits

Overall Test

Data Chi'Square Test Fisher's Exact Test
Number of chrom.:32 χ2=47200.792800
Number of traits:24 df=713
Number of QTLs:1,292 p-value=0

FOOT NOTE: * : FDR is short for "false discovery rate", representing the expected proportion of type I errors. A type I error is where you incorrectly reject the null hypothesis, i.e. you get a false positive. It's statistical definition is FDR = E(V/R | R > 0) P(R > 0), where V = Number of Type I errors (false positives); R = Number of rejected hypotheses. Benjamini–Hochberg procedure is a practical way to estimate FDR.

 

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