Release 57
(Aug 26, 2025)

Whole genome analysis for QTL/association enrichment

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Version: Enrich S: beta v0.8
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Data:

Number of milk composition - protein traits:37
Number of QTL / associations found:26,319
Number of chromosomes where QTL / associations are found:30

Chi-squared (χ2) test: are milk composition - protein traits over-represented on some chromosomes?

Chromosomes Total χ2 df p-values FDR * Size of χ2
Chromosome X22616.82646299e-419.310345e-41
Chromosome 1271.94741292.695085e-419.310345e-41
Chromosome 23127.15120299e-419.310345e-41
Chromosome 31043.54467295.383227e-2011.614968e-199
Chromosome 419576.28930299e-419.310345e-41
Chromosome 519.13418290.91779859.177985e-01
Chromosome 62187377.02822299e-419.310345e-41
Chromosome 77700.50808299e-419.310345e-41
Chromosome 814946.01310299e-419.310345e-41
Chromosome 915248.81185299e-419.310345e-41
Chromosome 107379.54048299e-419.310345e-41
Chromosome 1143167.51964299e-419.310345e-41
Chromosome 1218949.25030299e-419.310345e-41
Chromosome 134139.75240299e-419.310345e-41
Chromosome 14338657.99671299e-419.310345e-41
Chromosome 153931.03762299e-419.310345e-41
Chromosome 164008.67324299e-419.310345e-41
Chromosome 1714398.76904299e-419.310345e-41
Chromosome 1817291.01945299e-419.310345e-41
Chromosome 199810.43160299e-419.310345e-41
Chromosome 2093343.55153299e-419.310345e-41
Chromosome 2118443.80995299e-419.310345e-41
Chromosome 2216227.70716299e-419.310345e-41
Chromosome 233828.70450299e-419.310345e-41
Chromosome 2418332.41775299e-419.310345e-41
Chromosome 2517835.32793299e-419.310345e-41
Chromosome 2614251.29222299e-419.310345e-41
Chromosome 2727215.04956299e-419.310345e-41
Chromosome 2823805.66791299e-419.310345e-41
Chromosome 291954.97714299e-419.310345e-41

Chi-squared (χ2) test: Which of the 37 milk composition - protein traits are over-represented in the QTLdb

Traits Total χ2 df p-values FDR * Size of χ2
Milk alpha-S1-casein content 65.63037 36 0.001837388 3.399168e-03
Milk alpha-S1-casein percentage 155.33588 36 9.070768e-17 1.974226e-16
Milk alpha-S2-casein percentage 228.21408 36 8.639385e-30 2.458902e-29
Milk alpha-casein content 40.23639 36 0.288131 3.553616e-01
Milk alpha-casein percentage 42.09632 36 0.2238926 2.856561e-01
Milk alpha-casein to beta-casein ratio 4.51541 36 1 1.000000e+00
Milk alpha-lactalbumin content 8.51246 36 0.9999994 1.000000e+00
Milk alpha-lactalbumin percentage 183.93382 36 9.493755e-22 2.195431e-21
Milk beta-casein content 12.59626 36 0.9998966 1.000000e+00
Milk beta-casein percentage 476.941 36 2.142240e-78 3.963144e-77
Milk beta-lactoglobulin percentage 2291.20689 36 9e-41 2.775000e-40
Milk beta-lactoglobulin protein content 2379.62943 36 9e-41 2.775000e-40
Milk casein content 60.29444 36 0.00678569 1.046127e-02
Milk casein index 154.42055 36 1.298569e-16 2.669281e-16
Milk casein percentage 828.28579 36 1.25507e-150 4.643759e-149
Milk casein yield 63.20131 36 0.003373685 5.673925e-03
Milk delta-9-desaturase content 288.15427 36 4.238591e-41 2.775000e-40
Milk energy yield 59.85055 36 0.007528244 1.114180e-02
Milk glycosylated kappa-casein percentage 2004.67826 36 9e-41 2.775000e-40
Milk immunoglobulin G content 35.55415 36 0.4896334 5.844012e-01
Milk kappa-casein content 48.05076 36 0.086346 1.141001e-01
Milk kappa-casein percentage 2828.05345 36 9e-41 2.775000e-40
Milk lactoferrin content 2230.98835 36 9e-41 2.775000e-40
Milk lactoperoxidase content 54.98077 36 0.02229092 3.172169e-02
Milk osteopontin content 4.51541 36 1 1.000000e+00
Milk phosphorylated alpha-S2-casein percentage 447.23374 36 2.03753e-72 2.512954e-71
Milk protein content 61.46254 36 0.005144155 8.275380e-03
Milk protein percentage 5459.35097 36 9e-41 2.775000e-40
Milk protein yield 2363.54607 36 9e-41 2.775000e-40
Milk protein yield persistency 49.87934 36 0.06185948 8.477040e-02
Milk protein-to-fat ratio 78.5636 36 5.29323e-05 1.030787e-04
Milk unglycosylated kappa-casein percentage 2097.15661 36 9e-41 2.775000e-40
Milk urea nitrogen content 200.45403 36 1.040684e-24 2.750379e-24
Milk urea nitrogen yield 199.16353 36 1.780008e-24 4.390686e-24
Milk whey protein content 64.66383 36 0.002345796 4.133069e-03
Milk whey protein percentage 22.22571 36 0.9650477 1.000000e+00
Milk whey protein yield 2.2577 36 1 1.000000e+00

Correlations found between some of these traits for your reference

No correlation data found on these traits

Overall Test

Data Chi'Square Test Fisher's Exact Test
Number of chrom.:30 χ2=2968899.750600
Number of traits:37 df=1044
Number of QTLs:26,319 p-value=0

FOOT NOTE: * : FDR is short for "false discovery rate", representing the expected proportion of type I errors. A type I error is where you incorrectly reject the null hypothesis, i.e. you get a false positive. It's statistical definition is FDR = E(V/R | R > 0) P(R > 0), where V = Number of Type I errors (false positives); R = Number of rejected hypotheses. Benjamini–Hochberg procedure is a practical way to estimate FDR.

 

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